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Galaxolide possesses endocrine-disrupting activity and can exert anti-androgenic/estrogenic effects

Today, however, it is associated with hypertension, kidney disease, obesity and diabetes 17

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In the case of the control of GH secretion, it has been shown that -endorphin, administered intravenously or directly into the rat hypothalamus, increases GH secretion, an effect mediated by 2 -adrenergic pathways, stimulating GHRH and inhibiting SS release, because -endorphin antiserum reduced the stimulatory effect of clonidine on GH release [88]